Temperature dependence of mucin adsorption

The kinetics of adsorption and desorption on a silica-like surface of the large glycoprotein mucin have been measured across a range of temperatures from 25 to 60 degrees C. The area occupied per molecule diminishes with increasing temperature both in the bulk and adsorbed states, implying that the...

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Bibliographische Detailangaben
Veröffentlicht in:Langmuir : the ACS journal of surfaces and colloids. - 1992. - 24(2008), 3 vom: 05. Feb., Seite 902-5
1. Verfasser: McColl, James (VerfasserIn)
Weitere Verfasser: Yakubov, Gleb E, Ramsden, Jeremy J
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2008
Zugriff auf das übergeordnete Werk:Langmuir : the ACS journal of surfaces and colloids
Schlagworte:Journal Article Research Support, Non-U.S. Gov't Coated Materials, Biocompatible Mucins Silicon Dioxide 7631-86-9
Beschreibung
Zusammenfassung:The kinetics of adsorption and desorption on a silica-like surface of the large glycoprotein mucin have been measured across a range of temperatures from 25 to 60 degrees C. The area occupied per molecule diminishes with increasing temperature both in the bulk and adsorbed states, implying that the glycoprotein belongs to the "natively open" conformational class. Due to the conformational rearrangement, the specific interaction energy governing desorption greatly increases with temperature, resulting in an impressively regulated temperature-invariant dynamic surface coating
Beschreibung:Date Completed 02.04.2008
Date Revised 30.01.2008
published: Print-Electronic
Citation Status MEDLINE
ISSN:1520-5827
DOI:10.1021/la702550f