|
|
|
|
| LEADER |
01000naa a22002652 4500 |
| 001 |
NLM176655891 |
| 003 |
DE-627 |
| 005 |
20231223144516.0 |
| 007 |
cr uuu---uuuuu |
| 008 |
231223s2007 xx |||||o 00| ||eng c |
| 024 |
7 |
|
|a 10.1002/mrc.2123
|2 doi
|
| 028 |
5 |
2 |
|a pubmed24n0589.xml
|
| 035 |
|
|
|a (DE-627)NLM176655891
|
| 035 |
|
|
|a (NLM)18172904
|
| 040 |
|
|
|a DE-627
|b ger
|c DE-627
|e rakwb
|
| 041 |
|
|
|a eng
|
| 100 |
1 |
|
|a Goobes, Gil
|e verfasserin
|4 aut
|
| 245 |
1 |
4 |
|a The structure, dynamics, and energetics of protein adsorption-lessons learned from adsorption of statherin to hydroxyapatite
|
| 264 |
|
1 |
|c 2007
|
| 336 |
|
|
|a Text
|b txt
|2 rdacontent
|
| 337 |
|
|
|a ƒaComputermedien
|b c
|2 rdamedia
|
| 338 |
|
|
|a ƒa Online-Ressource
|b cr
|2 rdacarrier
|
| 500 |
|
|
|a Date Completed 09.09.2013
|
| 500 |
|
|
|a Date Revised 21.11.2013
|
| 500 |
|
|
|a published: Print
|
| 500 |
|
|
|a Citation Status MEDLINE
|
| 520 |
|
|
|a Copyright © 2007 John Wiley & Sons, Ltd.
|
| 520 |
|
|
|a Proteins are found to be involved in interaction with solid surfaces in numerous natural events. Acidic proteins that adsorb to crystal faces of a biomineral to control the growth and morphology of hard tissue are only one example. Deducing the mechanisms of surface recognition exercised by proteins has implications to osteogenesis, pathological calcification and other proteins functions at their adsorbed state. Statherin is an enamel pellicle protein that inhibits hydroxyapatite nucleation and growth, lubricates the enamel surface, and is recognized by oral bacteria in periodontal diseases. Here, we highlight some of the insights we obtained recently using both thermodynamic and solid state NMR measurements to the adsorption process of statherin to hydroxyapatite. We combine macroscopic energy characterization with microscopic structural findings to present our views of protein adsorption mechanisms and the structural changes accompanying it and discuss the implications of these studies to understanding the functions of the protein adsorbed to the enamel surfaces
|
| 650 |
|
4 |
|a Journal Article
|
| 650 |
|
4 |
|a Research Support, N.I.H., Extramural
|
| 650 |
|
4 |
|a Research Support, U.S. Gov't, Non-P.H.S.
|
| 650 |
|
4 |
|a Review
|
| 650 |
|
7 |
|a STATH protein, human
|2 NLM
|
| 650 |
|
7 |
|a Salivary Proteins and Peptides
|2 NLM
|
| 650 |
|
7 |
|a Durapatite
|2 NLM
|
| 650 |
|
7 |
|a 91D9GV0Z28
|2 NLM
|
| 700 |
1 |
|
|a Goobes, Rivka
|e verfasserin
|4 aut
|
| 700 |
1 |
|
|a Shaw, Wendy J
|e verfasserin
|4 aut
|
| 700 |
1 |
|
|a Gibson, James M
|e verfasserin
|4 aut
|
| 700 |
1 |
|
|a Long, Joanna R
|e verfasserin
|4 aut
|
| 700 |
1 |
|
|a Raghunathan, Vinodhkumar
|e verfasserin
|4 aut
|
| 700 |
1 |
|
|a Schueler-Furman, Ora
|e verfasserin
|4 aut
|
| 700 |
1 |
|
|a Popham, Jennifer M
|e verfasserin
|4 aut
|
| 700 |
1 |
|
|a Baker, David
|e verfasserin
|4 aut
|
| 700 |
1 |
|
|a Campbell, Charles T
|e verfasserin
|4 aut
|
| 700 |
1 |
|
|a Stayton, Patrick S
|e verfasserin
|4 aut
|
| 700 |
1 |
|
|a Drobny, Gary P
|e verfasserin
|4 aut
|
| 773 |
0 |
8 |
|i Enthalten in
|t Magnetic resonance in chemistry : MRC
|d 1985
|g 45 Suppl 1(2007) vom: 15. Dez., Seite S32-47
|w (DE-627)NLM098179667
|x 1097-458X
|7 nnns
|
| 773 |
1 |
8 |
|g volume:45 Suppl 1
|g year:2007
|g day:15
|g month:12
|g pages:S32-47
|
| 856 |
4 |
0 |
|u http://dx.doi.org/10.1002/mrc.2123
|3 Volltext
|
| 912 |
|
|
|a GBV_USEFLAG_A
|
| 912 |
|
|
|a SYSFLAG_A
|
| 912 |
|
|
|a GBV_NLM
|
| 912 |
|
|
|a GBV_ILN_350
|
| 951 |
|
|
|a AR
|
| 952 |
|
|
|d 45 Suppl 1
|j 2007
|b 15
|c 12
|h S32-47
|