Loricrin and involucrin expression is down-regulated by Th2 cytokines through STAT-6

Atopic dermatitis (AD) is characterized by a defective skin barrier which allows increased allergen and pathogen penetration. Loricrin (LOR) and involucrin (IVL) are proteins important for skin barrier formation and integrity. In this study, we demonstrate that the gene and protein expression of LOR...

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Veröffentlicht in:	Clinical immunology (Orlando, Fla.). - 1999. - 126(2008), 3 vom: 15. März, Seite 332-7
1. Verfasser:	Kim, Byung Eui (VerfasserIn)
Weitere Verfasser:	Leung, Donald Y M, Boguniewicz, Mark, Howell, Michael D
Format:	Online-Aufsatz
Sprache:	English
Veröffentlicht:	2008
Zugriff auf das übergeordnete Werk:	Clinical immunology (Orlando, Fla.)
Schlagworte:	Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't Cytokines Membrane Proteins Protein Precursors STAT6 Transcription Factor loricrin involucrin 60108-77-2