Morphological study of early-stage lung cancer using synchrotron radiation

In the present study the feasibility of applying synchrotron radiation to the morphological study of early-stage lung cancer has been investigated. Lewis lung cancer was implanted and grown in a nude mouse for different periods, and imaged using phase-contrast synchrotron X-rays. Morphological diffe...

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Détails bibliographiques
Publié dans:Journal of synchrotron radiation. - 1994. - 15(2008), Pt 1 vom: 01. Jan., Seite 36-42
Auteur principal: Liu, Ping (Auteur)
Autres auteurs: Sun, Jianqi, Guan, Yijing, Yue, Weisheng, Xu, Lisa X, Li, Yan, Zhang, Guilin, Hwu, Yeukuang, Je, Jung Ho, Margaritondo, G
Format: Article
Langue:English
Publié: 2008
Accès à la collection:Journal of synchrotron radiation
Sujets:Journal Article Research Support, Non-U.S. Gov't
Description
Résumé:In the present study the feasibility of applying synchrotron radiation to the morphological study of early-stage lung cancer has been investigated. Lewis lung cancer was implanted and grown in a nude mouse for different periods, and imaged using phase-contrast synchrotron X-rays. Morphological differences were clearly shown between the normal lung and cancerous tissues at this early stage. Irregular and tortuous angiogenesis were found in the periphery region of the developing lung cancer. Results from this study indicate that synchrotron X-rays can be used for imaging cancer development and progression with minimal invasion
Description:Date Completed 17.03.2008
Date Revised 24.11.2016
published: Print-Electronic
Citation Status MEDLINE
ISSN:1600-5775