Decrease of CD4(+)CD25(high)Foxp3(+) regulatory T cells and elevation of CD19(+)BAFF-R(+) B cells and soluble ICAM-1 in myasthenia gravis

Decrease of CD4(+)CD25(high)Foxp3(+) regulatory T cells and elevation of CD19(+)BAFF-R(+) B cells and soluble ICAM-1 in myasthenia gravis

Myasthenia gravis (MG) is caused by T-cell-dependent autoantibodies against muscle acetylcholine receptors (AChR) at the neuromuscular junction. Here, we adopted ELISA and flow cytometry techniques to measure the levels of Th1, Th2, Th3 cytokines, inflammatory cytokine and chemokine sICAM-1 and to a...

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Bibliographische Detailangaben
Veröffentlicht in:Clinical immunology (Orlando, Fla.). - 1999. - 126(2008), 2 vom: 01. Feb., Seite 180-8
1. Verfasser: Li, Xiang (VerfasserIn)
Weitere Verfasser: Xiao, Bao-Guo, Xi, Jian-Ying, Lu, Chuan-Zhen, Lu, Jia-Hong
Format: Aufsatz
Sprache:English
Veröffentlicht: 2008
Zugriff auf das übergeordnete Werk:Clinical immunology (Orlando, Fla.)
Schlagworte:Journal Article Research Support, Non-U.S. Gov't Adrenal Cortex Hormones Antigens, CD19 B-Cell Activation Factor Receptor CD4 Antigens Cytokines Interleukin-2 Receptor alpha Subunit TNFRSF13C protein, human Intercellular Adhesion Molecule-1 126547-89-5