Self-assembly of proximity probes for flexible and modular proximity ligation assays

Self-assembly of proximity probes for flexible and modular proximity ligation assays

Proximity ligation assay (PLA) is a recently developed strategy for protein analysis in which antibody-based detection of a target protein via a DNA ligation reaction of oligonucleotides linked to the antibodies results in the formation of an amplifiable DNA strand suitable for analysis. Here we des...

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Bibliographische Detailangaben
Veröffentlicht in:BioTechniques. - 1991. - 43(2007), 4 vom: 04. Okt., Seite 443-4, 446, 448 passim
1. Verfasser: Darmanis, Spyros (VerfasserIn)
Weitere Verfasser: Kähler, Anna, Spångberg, Lena, Kamali-Moghaddam, Masood, Landegren, Ulf, Schallmeiner, Edith
Format: Aufsatz
Sprache:English
Veröffentlicht: 2007
Zugriff auf das übergeordnete Werk:BioTechniques
Schlagworte:Journal Article Research Support, Non-U.S. Gov't Antibodies DNA Probes Proteins DNA Ligases EC 6.5.1.-