Thyrotropin receptor gene inactivating mutation in Chinese children with congenital hypothyroidism
OBJECTIVE: The inactivating mutation of thyrotropin receptor (TSHR) gene results in partial or complete insensitivity of thyrotropin (TSH) and dysfunction of the TSH-TSHR-cAMP cascade. Therefore, it may cause congenital hypothyroidism (CH). Depending on the degree of impairment of TSHR function, pat...
| Publié dans: | Zhonghua er ke za zhi = Chinese journal of pediatrics. - 1960. - 45(2007), 7 vom: 23. Juli, Seite 508-12 |
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| Auteur principal: | |
| Autres auteurs: | , , , |
| Format: | Article |
| Langue: | Chinese |
| Publié: |
2007
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| Accès à la collection: | Zhonghua er ke za zhi = Chinese journal of pediatrics |
| Sujets: | Journal Article Receptors, Thyrotropin Thyrotropin 9002-71-5 DNA 9007-49-2 |