Increased circulating interleukin (IL)-23 in children with malarial anemia in vivo and in vitro relationship with co-regulatory cytokines IL-12 and IL-10

Increased circulating interleukin (IL)-23 in children with malarial anemia : in vivo and in vitro relationship with co-regulatory cytokines IL-12 and IL-10

Severe malarial anemia (SMA) is a leading cause of mortality among children in sub-Saharan Africa. Although the novel cytokine, interleukin (IL)-23, promotes anemia in chronic inflammatory diseases, the role of IL-23 in SMA remains undefined. Since IL-23 and IL-12 share the IL-12p40 subunit and IL-1...

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Veröffentlicht in:Clinical immunology (Orlando, Fla.). - 1999. - 126(2008), 2 vom: 15. Feb., Seite 211-21
1. Verfasser: Ong'echa, John M (VerfasserIn)
Weitere Verfasser: Remo, Allison M, Kristoff, Jan, Hittner, James B, Were, Tom, Ouma, Collins, Otieno, Richard O, Vulule, John M, Keller, Christopher C, Awandare, Gordon A, Perkins, Douglas J
Format: Aufsatz
Sprache:English
Veröffentlicht: 2008
Zugriff auf das übergeordnete Werk:Clinical immunology (Orlando, Fla.)
Schlagworte:Journal Article Research Support, N.I.H., Extramural Hemeproteins Hemoglobins Interleukin-23 Protein Subunits Interleukin-10 130068-27-8 Interleukin-12 187348-17-0 mehr... hemozoin 39404-00-7