The clinical significance of leucocytosis and increase in interleukin content in acute mountain sickness complicated with multiple organ dysfunction syndrome

OBJECTIVE: To study the role of white blood cell (WBC) and interleukins (ILs) in acute mountain sickness (AMS) complicated with multiple organ dysfunction syndrome (MODS)

Bibliographische Detailangaben
Veröffentlicht in:Zhongguo wei zhong bing ji jiu yi xue = Chinese critical care medicine = Zhongguo weizhongbing jijiuyixue. - 1998. - 19(2007), 10 vom: 19. Okt., Seite 588-92
1. Verfasser: Zhou, Qi-quan (VerfasserIn)
Weitere Verfasser: Liu, Fu-yu, Zheng, Bi-hai, Gao, Yu-qi, Li, Su-zhi, Sun, Ze-ping, Zhang, Shi-fan
Format: Aufsatz
Sprache:Chinese
Veröffentlicht: 2007
Zugriff auf das übergeordnete Werk:Zhongguo wei zhong bing ji jiu yi xue = Chinese critical care medicine = Zhongguo weizhongbing jijiuyixue
Schlagworte:English Abstract Journal Article Research Support, Non-U.S. Gov't Interleukins
LEADER 01000caa a22002652 4500
001 NLM174470258
003 DE-627
005 20250208191608.0
007 tu
008 231223s2007 xx ||||| 00| ||chi c
028 5 2 |a pubmed25n0582.xml 
035 |a (DE-627)NLM174470258 
035 |a (NLM)17945078 
040 |a DE-627  |b ger  |c DE-627  |e rakwb 
041 |a chi 
100 1 |a Zhou, Qi-quan  |e verfasserin  |4 aut 
245 1 4 |a The clinical significance of leucocytosis and increase in interleukin content in acute mountain sickness complicated with multiple organ dysfunction syndrome 
264 1 |c 2007 
336 |a Text  |b txt  |2 rdacontent 
337 |a ohne Hilfsmittel zu benutzen  |b n  |2 rdamedia 
338 |a Band  |b nc  |2 rdacarrier 
500 |a Date Completed 08.10.2009 
500 |a Date Revised 19.10.2007 
500 |a published: Print 
500 |a Citation Status MEDLINE 
520 |a OBJECTIVE: To study the role of white blood cell (WBC) and interleukins (ILs) in acute mountain sickness (AMS) complicated with multiple organ dysfunction syndrome (MODS) 
520 |a METHODS: Three thousand one hundred and eighty-four patients suffering from severe AMC in the past 50 years were surveyed with questionnaire. Correlation analysis was done to explore the relationship between differential count of WBC and elevation of ILs contents and MODS 
520 |a RESULTS: There was no difference in differential count of WBC between essential high altitude pulmonary edema (HAPE) and secondary HAPE. No difference was also found between simple HAPE and high altitude cerebral edema (HACE). However, obvious difference in WBC was found between HACE accompanied by HAPE and simple HAPE or simple HACE in the differential counts of WBC, counts of WBC and neutrophil were significantly elevated, while lymphocyte was significantly declined (all P < 0.05). The count of WBC in people suffering from AMS accompanied by MODS was higher than patients only suffering from AMS, lymphocyte was significantly decreased, the difference was obviously (both P < 0.01). The content of tumor necrosis factor-alpha (TNF-alpha), IL-1, IL-2, IL-6 and IL-8 of severe AMS patients were obviously higher than that of normal people, therefore the content of IL-4 in severe AMS patients was obviously lower than that normal people the difference were obvious (all P < 0.01) 
520 |a CONCLUSION: People suffering from AMS also exist systemic inflammatory response syndrome (SIRS). SIRS play an important part in MODS which is a major cause of AMS, and it's a critical factor of high altitude MODS 
650 4 |a English Abstract 
650 4 |a Journal Article 
650 4 |a Research Support, Non-U.S. Gov't 
650 7 |a Interleukins  |2 NLM 
700 1 |a Liu, Fu-yu  |e verfasserin  |4 aut 
700 1 |a Zheng, Bi-hai  |e verfasserin  |4 aut 
700 1 |a Gao, Yu-qi  |e verfasserin  |4 aut 
700 1 |a Li, Su-zhi  |e verfasserin  |4 aut 
700 1 |a Sun, Ze-ping  |e verfasserin  |4 aut 
700 1 |a Zhang, Shi-fan  |e verfasserin  |4 aut 
773 0 8 |i Enthalten in  |t Zhongguo wei zhong bing ji jiu yi xue = Chinese critical care medicine = Zhongguo weizhongbing jijiuyixue  |d 1998  |g 19(2007), 10 vom: 19. Okt., Seite 588-92  |w (DE-627)NLM098227793  |x 1003-0603  |7 nnns 
773 1 8 |g volume:19  |g year:2007  |g number:10  |g day:19  |g month:10  |g pages:588-92 
912 |a GBV_USEFLAG_A 
912 |a SYSFLAG_A 
912 |a GBV_NLM 
912 |a GBV_ILN_350 
951 |a AR 
952 |d 19  |j 2007  |e 10  |b 19  |c 10  |h 588-92