Adhesion of giant vesicles mediated by weak binding of sialyl-LewisX to E-selectin in the presence of repelling poly(ethylene glycol) molecules

Prior to establishing tight contact with the endothelium, cells such as leukocytes or cancer cells use the recognition between sialyl-LewisX ligands and E-selectin receptors to establish weak, reversible adhesion and to roll along the vessel wall. We study the physical aspects of this process by con...

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Publié dans:Langmuir : the ACS journal of surfaces and colloids. - 1985. - 23(2007), 24 vom: 20. Nov., Seite 12293-300
Auteur principal: Lorz, Barbara G (Auteur)
Autres auteurs: Smith, Ana-S, Gege, Christian, Sackmann, Erich
Format: Article
Langue:English
Publié: 2007
Accès à la collection:Langmuir : the ACS journal of surfaces and colloids
Sujets:Journal Article Research Support, Non-U.S. Gov't Cell Adhesion Molecules E-Selectin Ligands Oligosaccharides Sialyl Lewis X Antigen Polyethylene Glycols 3WJQ0SDW1A