TNFalpha blockade in human diseases mechanisms and future directions

TNFalpha blockade in human diseases : mechanisms and future directions

Tumor necrosis factor-alpha (TNFalpha) antagonists have shown remarkable efficacy in a variety of immune-mediated inflammatory diseases (IMIDs). Therapeutic scope and limitations of these agents are reviewed in a recently published article in the Journal. In spite of their therapeutic popularity, li...

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Veröffentlicht in:Clinical immunology (Orlando, Fla.). - 1999. - 126(2008), 2 vom: 15. Feb., Seite 121-36
1. Verfasser: Wong, Maida (VerfasserIn)
Weitere Verfasser: Ziring, David, Korin, Yael, Desai, Sheetal, Kim, Sungjin, Lin, Jan, Gjertson, David, Braun, Jonathan, Reed, Elaine, Singh, Ram Raj
Format: Aufsatz
Sprache:English
Veröffentlicht: 2008
Zugriff auf das übergeordnete Werk:Clinical immunology (Orlando, Fla.)
Schlagworte:Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't Review Anti-Inflammatory Agents, Non-Steroidal Antibodies, Monoclonal Antibodies, Monoclonal, Humanized Antirheumatic Agents Cytokines Immunoglobulin G mehr... Receptors, Tumor Necrosis Factor Tumor Necrosis Factor-alpha Infliximab B72HH48FLU Adalimumab FYS6T7F842 Etanercept OP401G7OJC