The high prevalence of the I27 mutant HBcAg18-27 epitope in Chinese HBV-infected patients and its cross-reactivity with the V27 prototype epitope

The high prevalence of the I27 mutant HBcAg18-27 epitope in Chinese HBV-infected patients and its cross-reactivity with the V27 prototype epitope

HBcAg18-27 (FLPSDFFPSV, V27 epitope) is a dominant HLA-A2-restricted epitope in hepatitis B virus (HBV)-infected patients. So far, the occurrence of the epitope has not been assessed in China, where the prevalence of chronic HBV infection is high. In this report, we sequenced the HBV core gene in 10...

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Bibliographische Detailangaben
Veröffentlicht in:Clinical immunology (Orlando, Fla.). - 1999. - 125(2007), 3 vom: 15. Dez., Seite 337-45
1. Verfasser: Liu, Heng-Gui (VerfasserIn)
Weitere Verfasser: Chen, Wei-wei, Fan, Zhen-Ping, Yang, Hui-ying, Shi, Ming, Zhang, Zheng, Luan, Shen-Shun, Zhang, Hui, Lu, Peng, Tien, Po, Wang, Fu-Sheng
Format: Aufsatz
Sprache:English
Veröffentlicht: 2007
Zugriff auf das übergeordnete Werk:Clinical immunology (Orlando, Fla.)
Schlagworte:Journal Article Research Support, Non-U.S. Gov't Epitopes, T-Lymphocyte HLA-A2 Antigen Hepatitis B Core Antigens