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|a DE-627
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|c DE-627
|e rakwb
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|a eng
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1 |
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|a Xia, Xue-Kui
|e verfasserin
|4 aut
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| 245 |
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|a (1)H and (13)C NMR assignments for five anthraquinones from the mangrove endophytic fungus Halorosellinia sp. (No. 1403)
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|c 2007
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|a Text
|b txt
|2 rdacontent
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|a ohne Hilfsmittel zu benutzen
|b n
|2 rdamedia
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|a Band
|b nc
|2 rdacarrier
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|a Date Completed 06.12.2007
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|a Date Revised 22.10.2007
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|a published: Print
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|a Citation Status MEDLINE
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|a (c) 2007 John Wiley & Sons, Ltd.
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|a We report the unambiguous assignments of the (1)H and (13)C NMR spectra of two new natural products, namely, 1,4,5,6,7,9-hexahydroxy-2-methoxy-7-methyl-5beta,9beta,8abeta, 6alpha,10aalpha-hexahydroanthracen-10 (10aH)-one (1) and 1,4,6-trihydroxy-2-methoxy-7-methylanthracene-9, 10-dione (2), together with three known anthraquinones. These compounds were all isolated from the marine endophytic fungus No. 1403 collected from the South China Sea. Compounds 3 and 4 were isolated from the marine fungus for the first time. The structures were elucidated by the spectroscopic methods 1D and 2D NMR including COSY, HMQC, HMBC and NOE, and HREIMS. In our cytotoxicity assays, compound 5 showed cytotoxicity toward KB and KBv-200 cells with IC(50) of 1.40 and 2.58 microg/ml, respectively. In addition, the plausible biogenic relationship of compounds 1, 2, 3 and 4 is discussed
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|a Journal Article
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|a Research Support, Non-U.S. Gov't
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|a Anthraquinones
|2 NLM
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|a Carbon Isotopes
|2 NLM
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| 650 |
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|a Protons
|2 NLM
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| 700 |
1 |
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|a Huang, Hua-Rong
|e verfasserin
|4 aut
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|a She, Zhi-Gang
|e verfasserin
|4 aut
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| 700 |
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|a Shao, Chang-Lun
|e verfasserin
|4 aut
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| 700 |
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|a Liu, Fan
|e verfasserin
|4 aut
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| 700 |
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|a Cai, Xiao-Ling
|e verfasserin
|4 aut
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| 700 |
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|a Vrijmoed, L L P
|e verfasserin
|4 aut
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| 700 |
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|a Lin, Yong-Cheng
|e verfasserin
|4 aut
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| 773 |
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|i Enthalten in
|t Magnetic resonance in chemistry : MRC
|d 1985
|g 45(2007), 11 vom: 05. Nov., Seite 1006-9
|w (DE-627)NLM098179667
|x 1097-458X
|7 nnns
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| 773 |
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|g volume:45
|g year:2007
|g number:11
|g day:05
|g month:11
|g pages:1006-9
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