Supplementation with RD antigens enhances the protective efficacy of BCG in tuberculous mice

Supplementation with RD antigens enhances the protective efficacy of BCG in tuberculous mice

Different combinations of ESAT-6, CFP-10, CFP-21, MPT-64, encoded by RD1 and RD2 of Mycobacterium tuberculosis were evaluated on the basis of antigenicity in PPD positive TB contacts and immunogenicity in C57BL/6J mice immunized with the combination of all four RD antigens. The peripheral blood mono...

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Bibliographische Detailangaben
Veröffentlicht in:Clinical immunology (Orlando, Fla.). - 1999. - 125(2007), 2 vom: 15. Nov., Seite 173-83
1. Verfasser: Kalra, Mamta (VerfasserIn)
Weitere Verfasser: Grover, Ajay, Mehta, Neena, Singh, Jaspreet, Kaur, Jaspreet, Sable, Suraj B, Behera, Digambar, Sharma, Pawan, Verma, Indu, Khuller, G K
Format: Aufsatz
Sprache:English
Veröffentlicht: 2007
Zugriff auf das übergeordnete Werk:Clinical immunology (Orlando, Fla.)
Schlagworte:Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't Antigens, Bacterial BCG Vaccine Bacterial Proteins CFP-10 protein, Mycobacterium tuberculosis CFP21 protein, Mycobacterium tuberculosis ESAT-6 protein, Mycobacterium tuberculosis Interleukin-12 Subunit p40 mehr... MPT64 protein, Mycobacterium tuberculosis Interleukin-4 207137-56-2 Interferon-gamma 82115-62-6