CpG oligodeoxynucleotides induce cyclooxygenase-2 in human B lymphocytes : implications for adjuvant activity and antibody production
Synthetic CpG oligodeoxynucleotides (ODN), similar to DNA sequences found in certain microorganisms, have shown promise as adjuvants for humans by enhancing immune responses. Since antibodies are often indicators of successful vaccination, it is important to understand how CpG ODNs affect human B ce...
| Veröffentlicht in: | Clinical immunology (Orlando, Fla.). - 1999. - 125(2007), 2 vom: 15. Nov., Seite 138-48 |
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| Format: | Aufsatz |
| Sprache: | English |
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2007
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| Zugriff auf das übergeordnete Werk: | Clinical immunology (Orlando, Fla.) |
| Schlagworte: | Journal Article Research Support, N.I.H., Extramural Adjuvants, Immunologic Cyclooxygenase 2 Inhibitors Immunoglobulin G Immunoglobulin M Oligonucleotides Pyrazoles RNA, Messenger 1-((4-methylsulfonyl)phenyl)-3-trifluoromethyl-5-(4-fluorophenyl)pyrazole mehr... |