A high-frame rate high-frequency ultrasonic system for cardiac imaging in mice

We report the development of a high-frequency (30-50 MHz), real-time ultrasonic imaging system for cardiac imaging in mice. This system is capable of producing images at 130 frames per second (fps) with a spatial resolution of less than 50 microm. A novel mechanical sector probe was developed that u...

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Bibliographische Detailangaben
Veröffentlicht in:IEEE transactions on ultrasonics, ferroelectrics, and frequency control. - 1986. - 54(2007), 8 vom: 13. Aug., Seite 1648-55
1. Verfasser: Sun, Lei (VerfasserIn)
Weitere Verfasser: Richard, William D, Cannata, Jonathan M, Feng, Ching C, Johnson, Jeffrey A, Yen, Jesse T, Shung, K Kirk
Format: Aufsatz
Sprache:English
Veröffentlicht: 2007
Zugriff auf das übergeordnete Werk:IEEE transactions on ultrasonics, ferroelectrics, and frequency control
Schlagworte:Journal Article Research Support, N.I.H., Extramural
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520 |a We report the development of a high-frequency (30-50 MHz), real-time ultrasonic imaging system for cardiac imaging in mice. This system is capable of producing images at 130 frames per second (fps) with a spatial resolution of less than 50 microm. A novel mechanical sector probe was developed that utilizes a magnetic drive mechanism and custom-built servo controller for high speed and accuracy. Additionally, a very light-weight (< 0.28 g), single-element transducer was constructed and used to reduce the mass load on the motor. The imaging electronics were triggered according to the angular position of the transducer in order to compensate for the varying speed of the sector motor. This strategy ensured the production of equally spaced scan lines with minimal jitter. Wire phantom testing showed that the system axial and lateral resolutions were 48 microm and 72 microm, respectively. In vivo experiments showed that high-frequency ultrasonic imaging at 130 fps is capable of showing a detailed depiction of a beating mouse heart 
650 4 |a Journal Article 
650 4 |a Research Support, N.I.H., Extramural 
700 1 |a Richard, William D  |e verfasserin  |4 aut 
700 1 |a Cannata, Jonathan M  |e verfasserin  |4 aut 
700 1 |a Feng, Ching C  |e verfasserin  |4 aut 
700 1 |a Johnson, Jeffrey A  |e verfasserin  |4 aut 
700 1 |a Yen, Jesse T  |e verfasserin  |4 aut 
700 1 |a Shung, K Kirk  |e verfasserin  |4 aut 
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