High mobility group box 1 is increased in children with acute lymphocytic leukemia and stimulates the release of tumor necrosis factor-alpha in leukemic cell
OBJECTIVE: Cytokine mediated cell immunity is the main mode of anti-tumor immunity in organism, and the disequilibrium of cytokine network is the main cause of tumor cells escaping immunologic surveillance. High mobility group box 1 (HMGB1), a nuclear protein, has recently been identified as an impo...
Veröffentlicht in: | Zhonghua er ke za zhi = Chinese journal of pediatrics. - 1960. - 45(2007), 5 vom: 20. Mai, Seite 329-33 |
---|---|
1. Verfasser: | |
Weitere Verfasser: | , , , , |
Format: | Aufsatz |
Sprache: | Chinese |
Veröffentlicht: |
2007
|
Zugriff auf das übergeordnete Werk: | Zhonghua er ke za zhi = Chinese journal of pediatrics |
Schlagworte: | Journal Article Cytokines HMGB1 Protein Imidazoles Protein Kinase Inhibitors Pyridines Tumor Necrosis Factor-alpha JNK Mitogen-Activated Protein Kinases EC 2.7.11.24 Mitogen-Activated Protein Kinases mehr... |