High mobility group box 1 is increased in children with acute lymphocytic leukemia and stimulates the release of tumor necrosis factor-alpha in leukemic cell

OBJECTIVE: Cytokine mediated cell immunity is the main mode of anti-tumor immunity in organism, and the disequilibrium of cytokine network is the main cause of tumor cells escaping immunologic surveillance. High mobility group box 1 (HMGB1), a nuclear protein, has recently been identified as an impo...

Ausführliche Beschreibung

Bibliographische Detailangaben
Veröffentlicht in:Zhonghua er ke za zhi = Chinese journal of pediatrics. - 1960. - 45(2007), 5 vom: 20. Mai, Seite 329-33
1. Verfasser: Kang, Rui (VerfasserIn)
Weitere Verfasser: Tang, Dao-lin, Cao, Li-zhi, Yu, Yan, Zhang, Guo-yuan, Xiao, Xian-zhong
Format: Aufsatz
Sprache:Chinese
Veröffentlicht: 2007
Zugriff auf das übergeordnete Werk:Zhonghua er ke za zhi = Chinese journal of pediatrics
Schlagworte:Journal Article Cytokines HMGB1 Protein Imidazoles Protein Kinase Inhibitors Pyridines Tumor Necrosis Factor-alpha JNK Mitogen-Activated Protein Kinases EC 2.7.11.24 Mitogen-Activated Protein Kinases mehr... Mitogen-Activated Protein Kinase Kinases EC 2.7.12.2 SB 203580 OU13V1EYWQ