Amorphous drug nanosuspensions. 3. Particle dissolution and crystal growth

In the present paper, we have studied particle dissolution and crystal growth of the poorly water soluble drug felodipine, using fluorescence as a probe for the amount of crystalline material. Dissolution kinetics is essentially diffusion-controlled, while the rate of crystal growth is significantly...

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Détails bibliographiques
Publié dans:Langmuir : the ACS journal of surfaces and colloids. - 1985. - 23(2007), 19 vom: 11. Sept., Seite 9866-74
Auteur principal: Lindfors, Lennart (Auteur)
Autres auteurs: Skantze, Pia, Skantze, Urban, Westergren, Jan, Olsson, Ulf
Format: Article
Langue:English
Publié: 2007
Accès à la collection:Langmuir : the ACS journal of surfaces and colloids
Sujets:Journal Article Research Support, Non-U.S. Gov't Emulsions Surface-Active Agents Felodipine OL961R6O2C