Identification of biomolecular conformations from incomplete torsion angle observations by hidden Markov models

Identification of biomolecular conformations from incomplete torsion angle observations by hidden Markov models

We present a novel method for the identification of the most important conformations of a biomolecular system from molecular dynamics or Metropolis Monte Carlo time series by means of Hidden Markov Models (HMMs). We show that identification is possible based on the observation sequences of some esse...

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Veröffentlicht in:Journal of computational chemistry. - 1984. - 28(2007), 15 vom: 30. Nov., Seite 2453-64
1. Verfasser: Fischer, Alexander (VerfasserIn)
Weitere Verfasser: Waldhausen, Sonja, Horenko, Illia, Meerbach, Eike, Schütte, Christof
Format: Aufsatz
Sprache:English
Veröffentlicht: 2007
Zugriff auf das übergeordnete Werk:Journal of computational chemistry
Schlagworte:Journal Article Research Support, Non-U.S. Gov't Peptides DNA 9007-49-2 Alanine OF5P57N2ZX