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231223s2007 xx ||||| 00| ||eng c |
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|a pubmed24n0573.xml
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|a (DE-627)NLM171740688
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|a (NLM)17658858
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|a DE-627
|b ger
|c DE-627
|e rakwb
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| 041 |
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|a eng
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| 100 |
1 |
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|a Danoff, Emily J
|e verfasserin
|4 aut
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| 245 |
1 |
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|a Surfactant vesicles for high-efficiency capture and separation of charged organic solutes
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| 264 |
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1 |
|c 2007
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| 336 |
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|a Text
|b txt
|2 rdacontent
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| 337 |
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|a ohne Hilfsmittel zu benutzen
|b n
|2 rdamedia
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| 338 |
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|a Band
|b nc
|2 rdacarrier
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| 500 |
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|a Date Completed 17.09.2007
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|a Date Revised 08.08.2007
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|a published: Print-Electronic
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|a Citation Status MEDLINE
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|a We demonstrate the unique ability of catanionic vesicles, formed by mixing single-tailed cationic and anionic surfactants, to capture ionic solutes with remarkable efficiency. In an initial study (Wang, X.; Danoff, E. J.; Sinkov, N. A.; Lee, J.-H.; Raghavan, S. R.; English, D. S. Langmuir 2006, 22, 6461) with vesicles formed from cetyl trimethylammonium tosylate (CTAT) and sodium dodecylbenzenesulfonate (SDBS), we showed that CTAT-rich (cationic) vesicles could capture the anionic solute carboxyfluorescein with high efficiency (22%) and that the solute was retained by the vesicles for very long times (t1/2 = 84 days). Here we expand on these findings by investigating the interactions of both anionic and cationic solutes, including the chemotherapeutic agent doxorubicin, with both CTAT-rich and SDBS-rich vesicles. The ability of these vesicles to capture and hold dyes is extremely efficient (>20%) when the excess charge of the vesicle bilayer is opposite that of the solute (i.e., for anionic solutes in CTAT-rich vesicles and for cationic solutes in SDBS-rich vesicles). This charge-dependent effect is strong enough to enable the use of vesicles to selectively capture and separate an oppositely charged solute from a mixture of solutes. Our results suggest that catanionic surfactant vesicles could be useful for a variety of separation and drug delivery applications because of their unique properties and long-term stability
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| 650 |
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4 |
|a Journal Article
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| 650 |
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4 |
|a Research Support, U.S. Gov't, Non-P.H.S.
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| 650 |
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7 |
|a Organic Chemicals
|2 NLM
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| 650 |
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7 |
|a Surface-Active Agents
|2 NLM
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| 700 |
1 |
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|a Wang, Xiang
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Tung, Shih-Huang
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Sinkov, Nikolai A
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Kemme, Alice M
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Raghavan, Srinivasa R
|e verfasserin
|4 aut
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| 700 |
1 |
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|a English, Douglas S
|e verfasserin
|4 aut
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| 773 |
0 |
8 |
|i Enthalten in
|t Langmuir : the ACS journal of surfaces and colloids
|d 1992
|g 23(2007), 17 vom: 14. Aug., Seite 8965-71
|w (DE-627)NLM098181009
|x 1520-5827
|7 nnns
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| 773 |
1 |
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|g volume:23
|g year:2007
|g number:17
|g day:14
|g month:08
|g pages:8965-71
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