Temperature dependence of ligand-protein complex formation as reflected by saturation transfer difference NMR experiments

Temperature dependence of ligand-protein complex formation as reflected by saturation transfer difference NMR experiments

We show that temperature is an important parameter for the sensitivity of saturation transfer difference (STD) spectroscopy. A decreased intensity of STD signals is observed for lactose binding to growth-regulatory galectin7 (p53-induced gene 1), as well as for nucleotide binding to annexin A6, when...

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Veröffentlicht in:Magnetic resonance in chemistry : MRC. - 1985. - 45(2007), 9 vom: 01. Sept., Seite 745-8
1. Verfasser: Groves, Patrick (VerfasserIn)
Weitere Verfasser: Kövér, Katalin E, André, Sabine, Bandorowicz-Pikula, Joanna, Batta, Gyula, Bruix, Marta, Buchet, René, Canales, Angeles, Cañada, F Javier, Gabius, Hans-Joachim, Laurents, Douglas V, Naranjo, Jose R, Palczewska, Małgorzata, Pikula, Slawomir, Rial, Eduardo, Strzelecka-Kiliszek, Agnieszka, Jiménez-Barbero, Jesús
Format: Aufsatz
Sprache:English
Veröffentlicht: 2007
Zugriff auf das übergeordnete Werk:Magnetic resonance in chemistry : MRC
Schlagworte:Journal Article Research Support, Non-U.S. Gov't Annexin A6 Ion Channels Lectins Ligands Mitochondrial Proteins Proteins Protons UCP1 protein, human Uncoupling Protein 1