Cloning of the PpNHAD1 transporter of Physcomitrella patens, a chloroplast transporter highly conserved in photosynthetic eukaryotic organisms

A cDNA that encodes a transporter from the NHAD family was identified in Physcomitrella patens. Computer-based searches using the amino acid sequence of PpNHAD1 revealed that, in addition to being expressed in flowering plants, highly conserved transporters of this family are expressed in red algae,...

Ausführliche Beschreibung

Bibliographische Detailangaben
Veröffentlicht in:Journal of experimental botany. - 1985. - 58(2007), 11 vom: 01., Seite 2839-49
1. Verfasser: Barrero-Gil, Javier (VerfasserIn)
Weitere Verfasser: Rodríguez-Navarro, Alonso, Benito, Begoña
Format: Aufsatz
Sprache:English
Veröffentlicht: 2007
Zugriff auf das übergeordnete Werk:Journal of experimental botany
Schlagworte:Journal Article Research Support, N.I.H., Extramural Plant Proteins Recombinant Fusion Proteins Green Fluorescent Proteins 147336-22-9 Lithium 9FN79X2M3F Potassium RWP5GA015D
LEADER 01000caa a22002652c 4500
001 NLM171350421
003 DE-627
005 20250208112414.0
007 tu
008 231223s2007 xx ||||| 00| ||eng c
028 5 2 |a pubmed25n0571.xml 
035 |a (DE-627)NLM171350421 
035 |a (NLM)17617660 
040 |a DE-627  |b ger  |c DE-627  |e rakwb 
041 |a eng 
100 1 |a Barrero-Gil, Javier  |e verfasserin  |4 aut 
245 1 0 |a Cloning of the PpNHAD1 transporter of Physcomitrella patens, a chloroplast transporter highly conserved in photosynthetic eukaryotic organisms 
264 1 |c 2007 
336 |a Text  |b txt  |2 rdacontent 
337 |a ohne Hilfsmittel zu benutzen  |b n  |2 rdamedia 
338 |a Band  |b nc  |2 rdacarrier 
500 |a Date Completed 29.01.2008 
500 |a Date Revised 21.11.2013 
500 |a published: Print-Electronic 
500 |a Citation Status MEDLINE 
520 |a A cDNA that encodes a transporter from the NHAD family was identified in Physcomitrella patens. Computer-based searches using the amino acid sequence of PpNHAD1 revealed that, in addition to being expressed in flowering plants, highly conserved transporters of this family are expressed in red algae, green algae, mosses, liverworts, and photosynthetic stramenopiles, but not in heterotrophic stramenopiles. A chloroplast transit peptide was detected in PpNHAD1 and in most of the related sequences, indicating that PpNHAD1 is a chloroplast transporter. A PpNHAD1-GFP fusion localized to the chloroplast in Physcomitrella protoplasts, and truncation of the N-terminus of the protein dispersed the fluorescence signal outside the chloroplast. PpNHAD1 did not show functional expression in either yeast or bacterial mutants, but truncated proteins with shorter N-termini, PpNHAD1-1 and PpNHAD1-2, could be functionally expressed in bacteria. PpNHAD1-1 alleviated the Li(+) intolerance of a Na(+)-efflux Escherichia coli mutant at acidic pH values. Both PpNHAD1-1 and PpNHAD1-2 reduced the K(+) requirements of a K(+)-influx E. coli mutant more actively at high pH values. PpNHAD1 seems to be an important transporter that mediates ionic homeostasis in chloroplasts from red algae to flowering plants 
650 4 |a Journal Article 
650 4 |a Research Support, N.I.H., Extramural 
650 7 |a Plant Proteins  |2 NLM 
650 7 |a Recombinant Fusion Proteins  |2 NLM 
650 7 |a Green Fluorescent Proteins  |2 NLM 
650 7 |a 147336-22-9  |2 NLM 
650 7 |a Lithium  |2 NLM 
650 7 |a 9FN79X2M3F  |2 NLM 
650 7 |a Potassium  |2 NLM 
650 7 |a RWP5GA015D  |2 NLM 
700 1 |a Rodríguez-Navarro, Alonso  |e verfasserin  |4 aut 
700 1 |a Benito, Begoña  |e verfasserin  |4 aut 
773 0 8 |i Enthalten in  |t Journal of experimental botany  |d 1985  |g 58(2007), 11 vom: 01., Seite 2839-49  |w (DE-627)NLM098182706  |x 1460-2431  |7 nnas 
773 1 8 |g volume:58  |g year:2007  |g number:11  |g day:01  |g pages:2839-49 
912 |a GBV_USEFLAG_A 
912 |a SYSFLAG_A 
912 |a GBV_NLM 
912 |a GBV_ILN_350 
951 |a AR 
952 |d 58  |j 2007  |e 11  |b 01  |h 2839-49