Correction of age-associated deficiency in germinal center response by immunization with immune complexes

In aging, both primary and secondary antibody responses are impaired. One of the most notable changes in age-associated immune deficiency is the diminished germinal center (GC) reaction. This impaired GC response reduces antibody affinity maturation, decreases memory B cell development, and prevents...

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Bibliographische Detailangaben
Veröffentlicht in:Clinical immunology (Orlando, Fla.). - 1999. - 124(2007), 2 vom: 31. Aug., Seite 131-7
1. Verfasser: Zheng, Biao (VerfasserIn)
Weitere Verfasser: Switzer, Kirsten, Marinova, Ekaterina, Wansley, Daniel, Han, Shuhua
Format: Aufsatz
Sprache:English
Veröffentlicht: 2007
Zugriff auf das übergeordnete Werk:Clinical immunology (Orlando, Fla.)
Schlagworte:Journal Article Antigen-Antibody Complex Nitrophenols Phenylacetates 4-hydroxy-5-nitrophenyl acetic acid 10463-20-4