Correction of age-associated deficiency in germinal center response by immunization with immune complexes
In aging, both primary and secondary antibody responses are impaired. One of the most notable changes in age-associated immune deficiency is the diminished germinal center (GC) reaction. This impaired GC response reduces antibody affinity maturation, decreases memory B cell development, and prevents...
Veröffentlicht in: | Clinical immunology (Orlando, Fla.). - 1999. - 124(2007), 2 vom: 31. Aug., Seite 131-7 |
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1. Verfasser: | |
Weitere Verfasser: | , , , |
Format: | Aufsatz |
Sprache: | English |
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2007
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Zugriff auf das übergeordnete Werk: | Clinical immunology (Orlando, Fla.) |
Schlagworte: | Journal Article Antigen-Antibody Complex Nitrophenols Phenylacetates 4-hydroxy-5-nitrophenyl acetic acid 10463-20-4 |