A unique T cell subset described as CD4loCD40+ T cells (TCD40) in human type 1 diabetes

A unique T cell subset described as CD4loCD40+ T cells (TCD40) in human type 1 diabetes

Human T1D pancreatic lymph nodes contain diabetes-autoantigen responsive T cells but identification of such T cells in the periphery has proven difficult. Here we describe a unique T cell subset defined by CD4(lo) and CD40 expression (T(CD40)) that is significantly expanded in peripheral blood of T1...

Ausführliche Beschreibung

Bibliographische Detailangaben
Veröffentlicht in:Clinical immunology (Orlando, Fla.). - 1999. - 124(2007), 2 vom: 15. Aug., Seite 138-48
1. Verfasser: Waid, Dan M (VerfasserIn)
Weitere Verfasser: Wagner, Rebecca J, Putnam, Amy, Vaitaitis, Gisela M, Pennock, Nathan D, Calverley, David C, Gottlieb, Peter, Wagner, David H Jr
Format: Aufsatz
Sprache:English
Veröffentlicht: 2007
Zugriff auf das übergeordnete Werk:Clinical immunology (Orlando, Fla.)
Schlagworte:Journal Article Research Support, Non-U.S. Gov't Autoantigens CD40 Antigens HLA Antigens Platelet Membrane Glycoprotein IIb Receptors, Chemokine