High serum levels of BAFF, APRIL, and TACI in common variable immunodeficiency

High serum levels of BAFF, APRIL, and TACI in common variable immunodeficiency

Common variable immunodeficiency (CVID) is characterized by low levels of immune globulins and lack of antibody. Mutations in transmembrane activator and calcium-modulating cyclophilin ligand (TACI), are found in 8-10%, associated with autoimmunity and splenomegaly. Some patients with mutations had...

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Bibliographische Detailangaben
Veröffentlicht in:Clinical immunology (Orlando, Fla.). - 1999. - 124(2007), 2 vom: 15. Aug., Seite 182-9
1. Verfasser: Knight, Adina K (VerfasserIn)
Weitere Verfasser: Radigan, Lin, Marron, Thomas, Langs, Allison, Zhang, Li, Cunningham-Rundles, Charlotte
Format: Aufsatz
Sprache:English
Veröffentlicht: 2007
Zugriff auf das übergeordnete Werk:Clinical immunology (Orlando, Fla.)
Schlagworte:Journal Article Research Support, N.I.H., Extramural B-Cell Activating Factor RNA, Messenger TNFRSF13B protein, human TNFSF13B protein, human Transmembrane Activator and CAML Interactor Protein Tumor Necrosis Factor Ligand Superfamily Member 13