Molecular mechanics parameters for the FapydG DNA lesion

Molecular mechanics parameters for the FapydG DNA lesion

FapydG is a common oxidative DNA lesion involving opening of the imidazole ring. It shares the same precursor as 8-oxodG and can be excised by the same enzymes as 8-oxodG. However, the loss of the aromatic imidazole in FapydG results in a reduction of the double bond character between C5 and N7, wit...

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Veröffentlicht in:Journal of computational chemistry. - 1984. - 29(2008), 1 vom: 15. Jan., Seite 17-23
1. Verfasser: Song, Kun (VerfasserIn)
Weitere Verfasser: Hornak, Viktor, de los Santos, Carlos, Grollman, Arthur P, Simmerling, Carlos
Format: Aufsatz
Sprache:English
Veröffentlicht: 2008
Zugriff auf das übergeordnete Werk:Journal of computational chemistry
Schlagworte:Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't Bacterial Proteins