|
|
|
|
| LEADER |
01000naa a22002652 4500 |
| 001 |
NLM170499413 |
| 003 |
DE-627 |
| 005 |
20231223123633.0 |
| 007 |
tu |
| 008 |
231223s2007 xx ||||| 00| ||eng c |
| 028 |
5 |
2 |
|a pubmed24n0568.xml
|
| 035 |
|
|
|a (DE-627)NLM170499413
|
| 035 |
|
|
|a (NLM)17524808
|
| 040 |
|
|
|a DE-627
|b ger
|c DE-627
|e rakwb
|
| 041 |
|
|
|a eng
|
| 100 |
1 |
|
|a Mselle, Teddy F
|e verfasserin
|4 aut
|
| 245 |
1 |
0 |
|a Unique characteristics of NK cells throughout the human female reproductive tract
|
| 264 |
|
1 |
|c 2007
|
| 336 |
|
|
|a Text
|b txt
|2 rdacontent
|
| 337 |
|
|
|a ohne Hilfsmittel zu benutzen
|b n
|2 rdamedia
|
| 338 |
|
|
|a Band
|b nc
|2 rdacarrier
|
| 500 |
|
|
|a Date Completed 10.08.2007
|
| 500 |
|
|
|a Date Revised 01.12.2018
|
| 500 |
|
|
|a published: Print-Electronic
|
| 500 |
|
|
|a Citation Status MEDLINE
|
| 520 |
|
|
|a In this study, we have analyzed the presence and subsets of NK cells throughout the tissues of the FRT. We demonstrate that there are NK cells in the various FRT tissues and that their phenotype and regulation are largely dependent upon the FRT tissue where they reside. NK cells in the Fallopian tube, endometrium, cervix, and ectocervix expressed CD9 while blood NK cells did not. We have also found that unique subsets of NK cells are in specific locations of the FRT. The NK cells in the lower reproductive tract did not express CD94, but they did express CD16. In contrast, NK cells in the upper FRT express high amounts of CD94 and CD69, but few NK cells expressed CD16. All of these FRT NK cells were able to produce IFN-gamma upon stimulation with cytokines. Furthermore, the number of NK cells varied with the menstrual cycle in the endometrium but not in the cervix or ectocervix. These data suggest that unique characteristics of the tissues may account of specific localization of different NK cell subsets
|
| 650 |
|
4 |
|a Journal Article
|
| 650 |
|
4 |
|a Research Support, N.I.H., Extramural
|
| 650 |
|
7 |
|a Antigens, CD
|2 NLM
|
| 650 |
|
7 |
|a Antigens, Differentiation, T-Lymphocyte
|2 NLM
|
| 650 |
|
7 |
|a Antigens, Surface
|2 NLM
|
| 650 |
|
7 |
|a CD56 Antigen
|2 NLM
|
| 650 |
|
7 |
|a CD69 antigen
|2 NLM
|
| 650 |
|
7 |
|a CD9 protein, human
|2 NLM
|
| 650 |
|
7 |
|a Lectins, C-Type
|2 NLM
|
| 650 |
|
7 |
|a Membrane Glycoproteins
|2 NLM
|
| 650 |
|
7 |
|a NK Cell Lectin-Like Receptor Subfamily D
|2 NLM
|
| 650 |
|
7 |
|a Receptors, IgG
|2 NLM
|
| 650 |
|
7 |
|a Tetraspanin 29
|2 NLM
|
| 650 |
|
7 |
|a Leukocyte Common Antigens
|2 NLM
|
| 650 |
|
7 |
|a EC 3.1.3.48
|2 NLM
|
| 700 |
1 |
|
|a Meadows, Sarah K
|e verfasserin
|4 aut
|
| 700 |
1 |
|
|a Eriksson, Mikael
|e verfasserin
|4 aut
|
| 700 |
1 |
|
|a Smith, Jennifer M
|e verfasserin
|4 aut
|
| 700 |
1 |
|
|a Shen, Lilian
|e verfasserin
|4 aut
|
| 700 |
1 |
|
|a Wira, Charles R
|e verfasserin
|4 aut
|
| 700 |
1 |
|
|a Sentman, Charles L
|e verfasserin
|4 aut
|
| 773 |
0 |
8 |
|i Enthalten in
|t Clinical immunology (Orlando, Fla.)
|d 1999
|g 124(2007), 1 vom: 15. Juli, Seite 69-76
|w (DE-627)NLM098196855
|x 1521-7035
|7 nnns
|
| 773 |
1 |
8 |
|g volume:124
|g year:2007
|g number:1
|g day:15
|g month:07
|g pages:69-76
|
| 912 |
|
|
|a GBV_USEFLAG_A
|
| 912 |
|
|
|a SYSFLAG_A
|
| 912 |
|
|
|a GBV_NLM
|
| 912 |
|
|
|a GBV_ILN_11
|
| 912 |
|
|
|a GBV_ILN_24
|
| 912 |
|
|
|a GBV_ILN_350
|
| 951 |
|
|
|a AR
|
| 952 |
|
|
|d 124
|j 2007
|e 1
|b 15
|c 07
|h 69-76
|