Fabrication of biomolecular nanostructures by scanning near-field photolithography of oligo(ethylene glycol)-terminated self-assembled monolayers

The UV photo-oxidation of oligo(ethylene glycol) (OEG)-terminated self-assembled monolayers (SAMs) has been studied using static secondary ion mass spectrometry, X-ray photoelectron spectroscopy, contact angle measurement, and friction force microscopy. OEG-terminated SAMs are oxidized to yield sulf...

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Veröffentlicht in:Langmuir : the ACS journal of surfaces and colloids. - 1985. - 23(2007), 13 vom: 19. Juni, Seite 7328-37
1. Verfasser: Montague, Matthew (VerfasserIn)
Weitere Verfasser: Ducker, Robert E, Chong, Karen S L, Manning, Robert J, Rutten, Frank J M, Davies, Martyn C, Leggett, Graham J
Format: Aufsatz
Sprache:English
Veröffentlicht: 2007
Zugriff auf das übergeordnete Werk:Langmuir : the ACS journal of surfaces and colloids
Schlagworte:Journal Article Research Support, Non-U.S. Gov't Sulfhydryl Compounds Polyethylene Glycols 3WJQ0SDW1A Gold 7440-57-5
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245 1 0 |a Fabrication of biomolecular nanostructures by scanning near-field photolithography of oligo(ethylene glycol)-terminated self-assembled monolayers 
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520 |a The UV photo-oxidation of oligo(ethylene glycol) (OEG)-terminated self-assembled monolayers (SAMs) has been studied using static secondary ion mass spectrometry, X-ray photoelectron spectroscopy, contact angle measurement, and friction force microscopy. OEG-terminated SAMs are oxidized to yield sulfonates, but photodegradation of the OEG chain also occurs on a more rapid time scale, yielding degradation products that remain bound to the surface via gold-sulfur bonds. The oxidation of these degradation products is the rate-limiting step in the process. Photopatterning of OEG-terminated SAMs may be accomplished by using a mask and suitable light source or by using scanning near-field photolithography (SNP) in which the mask is replaced by a scanning near-field optical microscope coupled to a UV laser. Using SNP, it is possible to fabricate patterns in SAMs with a full width at half-maximum height (fwhm) as small as 9 nm, which is approximately 15 times smaller than the conventional diffraction limit. SNP-patterned OEG-terminated SAMs may be used to fabricate protein nanopatterns. By adsorbing carboxylic acid-terminated thiols into oxidized regions and converting these to active ester intermediates, it has been possible to fabricate lines of protein molecules with widths of only a few tens of nanometers 
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700 1 |a Ducker, Robert E  |e verfasserin  |4 aut 
700 1 |a Chong, Karen S L  |e verfasserin  |4 aut 
700 1 |a Manning, Robert J  |e verfasserin  |4 aut 
700 1 |a Rutten, Frank J M  |e verfasserin  |4 aut 
700 1 |a Davies, Martyn C  |e verfasserin  |4 aut 
700 1 |a Leggett, Graham J  |e verfasserin  |4 aut 
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