Radiation-induced apoptosis along with local and systemic cytokine elaboration is associated with DC plus radiotherapy-mediated renal cell tumor regression

Radiation-induced apoptosis along with local and systemic cytokine elaboration is associated with DC plus radiotherapy-mediated renal cell tumor regression

Utilizing melanoma and sarcoma tumor models syngeneic to C57BL/6 mice, we previously reported the antitumor effects of intratumoral (i.t.) administration of dendritic cells (DC) combined with localized radiotherapy (RT). However, the mechanisms underlying the augmented therapeutic effects have yet t...

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Bibliographische Detailangaben
Veröffentlicht in:Clinical immunology (Orlando, Fla.). - 1999. - 123(2007), 3 vom: 01. Juni, Seite 298-310
1. Verfasser: Huang, Jianhua (VerfasserIn)
Weitere Verfasser: Wang, Yao, Guo, Jia, Lu, Haiyan, Lin, Xingshi, Ma, Lin, Teitz-Tennenbaum, Seagal, Chang, Alfred E, Li, Qiao
Format: Aufsatz
Sprache:English
Veröffentlicht: 2007
Zugriff auf das übergeordnete Werk:Clinical immunology (Orlando, Fla.)
Schlagworte:Journal Article Research Support, Non-U.S. Gov't Antigens, CD Bak1 protein, mouse Bax protein, mouse Cytokines Immunoglobulin G Immunoglobulin M Proto-Oncogene Proteins c-bcl-2 Tumor Necrosis Factor-alpha mehr... bcl-2 Homologous Antagonist-Killer Protein bcl-2-Associated X Protein Granulocyte Colony-Stimulating Factor 143011-72-7 Interleukin-4 207137-56-2