A novel method for KIR-ligand typing by pyrosequencing to predict NK cell alloreactivity

Studies have shown that KIR-ligand mismatching to predict NK cell alloreactivity may result in less relapse and better survival in patients with AML. KIR-ligands are distinguished by single nucleotide polymorphisms (SNPs) from HLA-B and HLA-C sequences. We hypothesized that pyrosequencing to determi...

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Publié dans:	Clinical immunology (Orlando, Fla.). - 1999. - 123(2007), 3 vom: 01. Juni, Seite 272-80
Auteur principal:	Yun, Gong (Auteur)
Autres auteurs:	Tolar, Jakub, Yerich, Anton K, Marsh, Steven G E, Robinson, James, Noreen, Harriet, Blazar, Bruce R, Miller, Jeffrey S
Format:	Article
Langue:	English
Publié:	2007
Accès à la collection:	Clinical immunology (Orlando, Fla.)
Sujets:	Journal Article Research Support, N.I.H., Extramural HLA-B Antigens HLA-C Antigens Isoantigens Ligands Receptors, Immunologic Receptors, KIR