A novel method for KIR-ligand typing by pyrosequencing to predict NK cell alloreactivity

Studies have shown that KIR-ligand mismatching to predict NK cell alloreactivity may result in less relapse and better survival in patients with AML. KIR-ligands are distinguished by single nucleotide polymorphisms (SNPs) from HLA-B and HLA-C sequences. We hypothesized that pyrosequencing to determi...

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Bibliographische Detailangaben
Veröffentlicht in:Clinical immunology (Orlando, Fla.). - 1999. - 123(2007), 3 vom: 15. Juni, Seite 272-80
1. Verfasser: Yun, Gong (VerfasserIn)
Weitere Verfasser: Tolar, Jakub, Yerich, Anton K, Marsh, Steven G E, Robinson, James, Noreen, Harriet, Blazar, Bruce R, Miller, Jeffrey S
Format: Aufsatz
Sprache:English
Veröffentlicht: 2007
Zugriff auf das übergeordnete Werk:Clinical immunology (Orlando, Fla.)
Schlagworte:Journal Article Research Support, N.I.H., Extramural HLA-B Antigens HLA-C Antigens Isoantigens Ligands Receptors, Immunologic Receptors, KIR