Effects of rhubarb and different routes of nutrition support on invasive fungal infection

OBJECTIVE: To study the effects of rhubarb and the different routes of nutrition support on invasive fungal infection

Bibliographische Detailangaben
Veröffentlicht in:Zhongguo wei zhong bing ji jiu yi xue = Chinese critical care medicine = Zhongguo weizhongbing jijiuyixue. - 1998. - 19(2007), 3 vom: 22. März, Seite 150-2
1. Verfasser: Chen, De-chang (VerfasserIn)
Weitere Verfasser: Yang, Xing-yi, Zhao, Liang, Lin, Zhao-fen, Shan, Hong-wei, Li, Wen-fang, Guo, Chang-xing
Format: Aufsatz
Sprache:Chinese
Veröffentlicht: 2007
Zugriff auf das übergeordnete Werk:Zhongguo wei zhong bing ji jiu yi xue = Chinese critical care medicine = Zhongguo weizhongbing jijiuyixue
Schlagworte:English Abstract Journal Article Randomized Controlled Trial Research Support, Non-U.S. Gov't
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245 1 0 |a Effects of rhubarb and different routes of nutrition support on invasive fungal infection 
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500 |a Date Completed 09.07.2009 
500 |a Date Revised 22.03.2007 
500 |a published: Print 
500 |a Citation Status MEDLINE 
520 |a OBJECTIVE: To study the effects of rhubarb and the different routes of nutrition support on invasive fungal infection 
520 |a METHODS: One thousand and ninety patients, who suffered from sepsis subsequent to trauma, shock and infection were enrolled in this study. The patients were randomly divided into two groups, 637 cases in rhubarb preventive treatment group and 453 cases in non-preventive rhubarb treatment group. They were again divided into four subgroups: enteral nutrition support, and no nutrition support group. The incidence of invasive fungal infection was observed in those groups 
520 |a RESULTS: The incidence of invasive fungal infection in rhubarb preventive treatment group (3.0%) was much lower than that in non-preventive rhubarb treatment group (11.5%). There was significant difference between two groups (P<0.05). Furthermore, fewer patients developed invasive fungal infection in enteral nutrition support and enteral combined parenteral nutrition support subgroups after preventive rhubarb treatment (0.9% and 2.1%), compared with parenteral nutrition support and no nutrition support subgroups (30.4% and 61.3%) and corresponding subgroups with non-preventive treatment of rhubarb (3.9% and 7.1%, P<0.05 or P<0.01). In addition, the route of nutrition support also affected the incidence of invasive fungal infection. Patients in enteral nutrition support and enteral combined parenteral nutrition support subgroups had lower incidence of invasive fungal infection than in parenteral nutrition support and no nutrition support subgroups (all P<0.05), and the incidence was the highest in no nutrition support subgroup. There were no significant difference between parenteral nutrition support and no nutrition support subgroups 
520 |a CONCLUSION: Rhubarb and enteral nutrition support have preventive effects on invasive fungal infection via gut mechanism 
650 4 |a English Abstract 
650 4 |a Journal Article 
650 4 |a Randomized Controlled Trial 
650 4 |a Research Support, Non-U.S. Gov't 
700 1 |a Yang, Xing-yi  |e verfasserin  |4 aut 
700 1 |a Zhao, Liang  |e verfasserin  |4 aut 
700 1 |a Lin, Zhao-fen  |e verfasserin  |4 aut 
700 1 |a Shan, Hong-wei  |e verfasserin  |4 aut 
700 1 |a Li, Wen-fang  |e verfasserin  |4 aut 
700 1 |a Guo, Chang-xing  |e verfasserin  |4 aut 
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