Cell surface CCR5 density determines the intensity of T cell migration towards rheumatoid arthritis synoviocytes

Cell surface CCR5 density determines the intensity of T cell migration towards rheumatoid arthritis synoviocytes

As we have recently shown that the number of CCR5 molecules at the cell surface determines the efficiency of its function as a chemokine receptor, we tested the hypothesis that cell surface CCR5 density could influence the intensity of T lymphocyte recruitment into the rheumatoid joint. For this pur...

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Détails bibliographiques
Publié dans:Clinical immunology (Orlando, Fla.). - 1999. - 123(2007), 2 vom: 23. Mai, Seite 148-54
Auteur principal: Desmetz, Caroline (Auteur)
Autres auteurs: Lin, Yea-Lih, Mettling, Clément, Portalès, Pierre, Noël, Danièle, Clot, Jacques, Jorgensen, Christian, Corbeau, Pierre
Format: Article
Langue:English
Publié: 2007
Accès à la collection:Clinical immunology (Orlando, Fla.)
Sujets:Journal Article Antibodies, Monoclonal CCL5 protein, human CXCL12 protein, human Chemokine CCL5 Chemokine CXCL12 Chemokines, CC Chemokines, CXC Culture Media, Conditioned Receptors, CCR5 plus... Receptors, CXCR4 Tumor Necrosis Factor-alpha