Structural stability against disintegration by anionic lipids rationalizes the efficiency of cationic liposome/DNA complexes

Reported here is the correlation between the transfection efficiency of cationic liposome/DNA complexes (lipoplexes) and the structural evolution that they undergo when interacting with anionic membrane lipids. Multicomponent lipoplexes, incorporating from three to six lipid species simultaneously,...

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Veröffentlicht in:Langmuir : the ACS journal of surfaces and colloids. - 1992. - 23(2007), 8 vom: 10. Apr., Seite 4498-508
1. Verfasser: Caracciolo, Giulio (VerfasserIn)
Weitere Verfasser: Marchini, Cristina, Pozzi, Daniela, Caminiti, Ruggero, Amenitsch, Heinz, Montani, Maura, Amici, Augusto
Format: Aufsatz
Sprache:English
Veröffentlicht: 2007
Zugriff auf das übergeordnete Werk:Langmuir : the ACS journal of surfaces and colloids
Schlagworte:Journal Article Anions Cations Lipids Liposomes Phosphatidylglycerols 1,2-dioleoyl-sn-glycero-3-phosphoglycerol 66322-31-4 DNA 9007-49-2