Effects of estrogen receptor subtype-selective agonists on autoimmune disease in lupus-prone NZB/NZW F1 mouse model

Effects of estrogen receptor subtype-selective agonists on autoimmune disease in lupus-prone NZB/NZW F1 mouse model

The specific roles of estrogen receptor (ER) subtypes alpha and beta in mediating estrogen's influences on lupus autoimmunity are unknown. Herein we found that ovariectomized NZB/NZW F1 mice treated with propyl pyrazole triol (ERalpha-selective agonist) had significantly shorter survival, earli...

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Bibliographische Detailangaben
Veröffentlicht in:Clinical immunology (Orlando, Fla.). - 1999. - 123(2007), 2 vom: 31. Mai, Seite 219-26
1. Verfasser: Li, Jing (VerfasserIn)
Weitere Verfasser: McMurray, Robert W
Format: Aufsatz
Sprache:English
Veröffentlicht: 2007
Zugriff auf das übergeordnete Werk:Clinical immunology (Orlando, Fla.)
Schlagworte:Journal Article 2,3-bis(4-hydroxyphenyl)-propionitrile Antibodies, Antinuclear Estrogen Receptor alpha Estrogen Receptor beta Immunoglobulin G Immunologic Factors Nitriles Phenols Propionates mehr... Pyrazoles Receptors, Estrogen 4,4',4''-(4-propyl-((1)H)-pyrazole-1,3,5-triyl) tris-phenol 0T83Y6JZPF estradiol 3-benzoate 1S4CJB5ZGN Estradiol 4TI98Z838E Prolactin 9002-62-4