Soluble CTLA-4 in autoimmune thyroid diseases relationship with clinical status and possible role in the immune response dysregulation

Soluble CTLA-4 in autoimmune thyroid diseases : relationship with clinical status and possible role in the immune response dysregulation

CTLA-4 molecule, expressed by activated T and B lymphocytes, transduces an inhibitory signal. Increasing evidence showed CTLA-4 gene as an important susceptibility locus for autoimmune endocrinopathies and other autoimmune disorders. The aim is to evaluate the augmented sCTLA-4 serum levels in diffe...

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Bibliographische Detailangaben
Veröffentlicht in:Clinical immunology (Orlando, Fla.). - 1999. - 123(2007), 2 vom: 15. Mai, Seite 190-8
1. Verfasser: Saverino, Daniele (VerfasserIn)
Weitere Verfasser: Brizzolara, Renata, Simone, Rita, Chiappori, Alessandra, Milintenda-Floriani, Francesca, Pesce, Giampaola, Bagnasco, Marcello
Format: Aufsatz
Sprache:English
Veröffentlicht: 2007
Zugriff auf das übergeordnete Werk:Clinical immunology (Orlando, Fla.)
Schlagworte:Journal Article Research Support, Non-U.S. Gov't Antigens, CD Antigens, Differentiation B7-1 Antigen B7-2 Antigen CD28 Antigens CTLA-4 Antigen CTLA4 protein, human