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231223s2007 xx ||||| 00| ||eng c |
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|a pubmed24n0562.xml
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|a (DE-627)NLM16851821X
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|a (NLM)17311430
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|a DE-627
|b ger
|c DE-627
|e rakwb
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|a eng
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| 100 |
1 |
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|a Shiotani, Atsushi
|e verfasserin
|4 aut
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| 245 |
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|a Stable incorporation of gold nanorods into N-isopropylacrylamide hydrogels and their rapid shrinkage induced by near-infrared laser irradiation
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|c 2007
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|a Text
|b txt
|2 rdacontent
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|a ohne Hilfsmittel zu benutzen
|b n
|2 rdamedia
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|a Band
|b nc
|2 rdacarrier
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| 500 |
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|a Date Completed 15.05.2007
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|a Date Revised 09.03.2022
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|a published: Print-Electronic
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|a Citation Status PubMed-not-MEDLINE
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|a In this study, we prepared gold nanorod (NR)-embedded N-isopropylacrylamide (NIPAM) hydrogels and studied their volume phase transition behavior induced by near-infrared (near-IR) laser irradiation utilizing the photothermal conversion characteristics of the NRs. When poly(ethylene glycol)-modified NRs were used for the preparation of composite gels, the NRs showed marked dispersion stability in the gel. Near-IR laser irradiation of the gel (cylindrical shape, diameter = 140 microm) under the following conditions, NR concentrations in the gel > or =100 microM and laser irradiation power > or =490 mW, resulted in shrinkage of the gel in the following manner: (1) waist formation around the irradiation spot and (2) growth of the waist along the axial directions of the gel. The gel shrinking induced by near-IR irradiation occurred much more rapidly than that afforded by a temperature jump, because the former was not accompanied by the skin layer formation, which disturbs the rapid shrinking of the gels. When a composite gel containing the model drug (rhodamine-labeled dextran) was irradiated with a near-IR laser, the rapid release of the drug was observed. Taking advantage of the high spatial resolution of the irradiation point, we further achieved the irradiation-point-specific release of the drug from one such gel
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|a Journal Article
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1 |
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|a Mori, Takeshi
|e verfasserin
|4 aut
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| 700 |
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|a Niidome, Takuro
|e verfasserin
|4 aut
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| 700 |
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|a Niidome, Yasuro
|e verfasserin
|4 aut
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| 700 |
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|a Katayama, Yoshiki
|e verfasserin
|4 aut
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| 773 |
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|i Enthalten in
|t Langmuir : the ACS journal of surfaces and colloids
|d 1992
|g 23(2007), 7 vom: 27. März, Seite 4012-8
|w (DE-627)NLM098181009
|x 1520-5827
|7 nnns
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| 773 |
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|g volume:23
|g year:2007
|g number:7
|g day:27
|g month:03
|g pages:4012-8
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|d 23
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