Supramolecular complex induced by the binding of sodium dodecyl sulfate to PAMAM dendrimers
Isothermal titration calorimetry (ITC) and dynamic light scattering (DLS) were employed to study the spontaneous supramolecular complexation of amine terminated PAMAM dendrimer (G3[EDA] PAMAM-NH2) induced by the binding of an anionic surfactant, sodium dodecyl sulfate (SDS). At pH<or=2, SDS molec...
| Veröffentlicht in: | Langmuir : the ACS journal of surfaces and colloids. - 1992. - 23(2007), 4 vom: 13. Feb., Seite 1635-9 |
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| Weitere Verfasser: | , , |
| Format: | Aufsatz |
| Sprache: | English |
| Veröffentlicht: |
2007
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| Zugriff auf das übergeordnete Werk: | Langmuir : the ACS journal of surfaces and colloids |
| Schlagworte: | Journal Article Research Support, Non-U.S. Gov't Dendrimers PAMAM Starburst Polyamines Sodium Dodecyl Sulfate 368GB5141J |
| Zusammenfassung: | Isothermal titration calorimetry (ITC) and dynamic light scattering (DLS) were employed to study the spontaneous supramolecular complexation of amine terminated PAMAM dendrimer (G3[EDA] PAMAM-NH2) induced by the binding of an anionic surfactant, sodium dodecyl sulfate (SDS). At pH<or=2, SDS molecules bound to protonated amines on the outer rims of G3[EDA] PAMAM-NH2 driven by electrostatic interaction, which induced the formation of PAMAM/SDS supramolecular complex via hydrophobic association between bound SDS molecules. The complex with radius of approximately 37 nm was observed at SDS concentration as low as 0.02 mM (in 0.2 mM PAMAM). The size of the complex increased progressively with increasing SDS concentration and precipitated when the SDS concentration exceeded 15 mM. At pH of approximately 7.4, the formation of PAMAM/SDS complex was observed at higher SDS concentration (0.1 mM in 0.2 mM PAMAM), and it resolubilized with further increase of SDS concentration to approximately 18 mM due to weaker electrostatic interaction at higher pH. At pH>or=10, the electrostatic binding ceased because the deprotonated PAMAM dendrimer was uncharged, and hence the surfactant-induced supramolecular assembly could not be formed |
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| Beschreibung: | Date Completed 02.05.2007 Date Revised 21.11.2013 published: Print-Electronic Citation Status MEDLINE |
| ISSN: | 1520-5827 |