Soluble TNF-alpha receptor 2 produced by alternative splicing is paradoxically associated with markers of liver injury

Soluble TNF-alpha receptor 2 produced by alternative splicing is paradoxically associated with markers of liver injury

Tumor necrosis factor-alpha and insulin resistance play central roles in the pathogenesis of abnormal hepatocellular function. We evaluate the relationship between a novel serum DS-TNFR2 (an alternatively spliced soluble TNF-alpha receptor 2) isoform and parameters of liver health. Serum ALT, AST an...

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Veröffentlicht in:Clinical immunology (Orlando, Fla.). - 1999. - 123(2007), 1 vom: 01. Apr., Seite 89-94
1. Verfasser: Esteve, Eduardo (VerfasserIn)
Weitere Verfasser: Botas, Patricia, Delgado, Elías, López-Bermejo, Abel, Lainez, Begoña, Engel, Pablo, Ricart, Wifredo, Fernández-Real, Jose-Manuel
Format: Aufsatz
Sprache:English
Veröffentlicht: 2007
Zugriff auf das übergeordnete Werk:Clinical immunology (Orlando, Fla.)
Schlagworte:Journal Article Research Support, Non-U.S. Gov't Adiponectin Biomarkers Protein Isoforms Receptors, Tumor Necrosis Factor, Type II gamma-Glutamyltransferase EC 2.3.2.2 Aspartate Aminotransferases EC 2.6.1.1 mehr... Alanine Transaminase EC 2.6.1.2