Increased expression of the FoxP3 functional marker of regulatory T cells following B cell depletion with rituximab in patients with lupus nephritis

Increased expression of the FoxP3 functional marker of regulatory T cells following B cell depletion with rituximab in patients with lupus nephritis

B cell depletion may affect T cell activation and costimulation status in rituximab-treated patients with SLE. We examined whether rituximab administration in patients with active lupus nephritis is related to changes in mRNA expression of genes that define regulatory T cells (Tregs) in peripheral b...

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Bibliographische Detailangaben
Veröffentlicht in:Clinical immunology (Orlando, Fla.). - 1999. - 123(2007), 1 vom: 01. Apr., Seite 66-73
1. Verfasser: Sfikakis, P P (VerfasserIn)
Weitere Verfasser: Souliotis, V L, Fragiadaki, K G, Moutsopoulos, H M, Boletis, J N, Theofilopoulos, A N
Format: Aufsatz
Sprache:English
Veröffentlicht: 2007
Zugriff auf das übergeordnete Werk:Clinical immunology (Orlando, Fla.)
Schlagworte:Journal Article Research Support, Non-U.S. Gov't Antibodies, Monoclonal Antibodies, Monoclonal, Murine-Derived FOXP3 protein, human Forkhead Transcription Factors Immunologic Factors RNA, Messenger Transforming Growth Factor beta CD40 Ligand mehr... 147205-72-9 Rituximab 4F4X42SYQ6