A novel method to fabricate patterned bilayer lipid membranes

We introduce a new method for forming tethered bilayer lipid membranes on surfaces patterned using a photocleavable self-assembled monolayer (SAM). A SAM terminated with a hydrophobic fluorocarbon residue was bound to a gold surface through a link containing a photocleavable ortho-nitrobenzyl moiety...

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Bibliographische Detailangaben
Veröffentlicht in:Langmuir : the ACS journal of surfaces and colloids. - 1992. - 23(2007), 3 vom: 30. Jan., Seite 1354-8
1. Verfasser: Han, Xiaojun (VerfasserIn)
Weitere Verfasser: Critchley, Kevin, Zhang, Lixin, Pradeep, Singh N D, Bushby, Richard J, Evans, Stephen D
Format: Aufsatz
Sprache:English
Veröffentlicht: 2007
Zugriff auf das übergeordnete Werk:Langmuir : the ACS journal of surfaces and colloids
Schlagworte:Journal Article Research Support, Non-U.S. Gov't Cross-Linking Reagents Lipid Bilayers Liposomes Phosphatidylcholines Gold 7440-57-5
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245 1 2 |a A novel method to fabricate patterned bilayer lipid membranes 
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520 |a We introduce a new method for forming tethered bilayer lipid membranes on surfaces patterned using a photocleavable self-assembled monolayer (SAM). A SAM terminated with a hydrophobic fluorocarbon residue was bound to a gold surface through a link containing a photocleavable ortho-nitrobenzyl moiety. Hydrophilic regions were produced by irradiation with soft UV (365 nm) through a photomask. The patterned surface was characterized by scanning electron microscopy and electrochemical impedance spectroscopy. Tethered bilayer lipid membranes with well-defined bilayer and monolayer regions were then formed by exposure to egg PC vesicles. The membranes had resistance and capacitance values of 0.52 MOmega.cm2 and 0.83 microF.cm-2, respectively 
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650 4 |a Research Support, Non-U.S. Gov't 
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700 1 |a Critchley, Kevin  |e verfasserin  |4 aut 
700 1 |a Zhang, Lixin  |e verfasserin  |4 aut 
700 1 |a Pradeep, Singh N D  |e verfasserin  |4 aut 
700 1 |a Bushby, Richard J  |e verfasserin  |4 aut 
700 1 |a Evans, Stephen D  |e verfasserin  |4 aut 
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