Two-dimensional densely packed DNA nanostructure derived from DNA complexation with a low-generation poly(amidoamine) dendrimer

One of the keys for using deoxyribonucleic acid (DNA) as a nanomaterial relies on how the individual DNA chain can be aligned and how a multitude of DNA chains can be packed into ordered nanostructures. Here we present a simple method for constructing a 2-D densely packed DNA nanostructure using the...

Ausführliche Beschreibung

Bibliographische Detailangaben
Veröffentlicht in:Langmuir : the ACS journal of surfaces and colloids. - 1992. - 23(2007), 3 vom: 30. Jan., Seite 975-8
1. Verfasser: Su, Chun-Jen (VerfasserIn)
Weitere Verfasser: Liu, Yi-Chun, Chen, Hsin-Lung, Li, Yen-Cheng, Lin, Hsien-Kuang, Liu, Wen-Liang, Hsu, Chain-Shu
Format: Aufsatz
Sprache:English
Veröffentlicht: 2007
Zugriff auf das übergeordnete Werk:Langmuir : the ACS journal of surfaces and colloids
Schlagworte:Journal Article Research Support, Non-U.S. Gov't Amines Dendrimers Polymers DNA 9007-49-2
LEADER 01000naa a22002652 4500
001 NLM167860135
003 DE-627
005 20231223113851.0
007 tu
008 231223s2007 xx ||||| 00| ||eng c
028 5 2 |a pubmed24n0560.xml 
035 |a (DE-627)NLM167860135 
035 |a (NLM)17240998 
040 |a DE-627  |b ger  |c DE-627  |e rakwb 
041 |a eng 
100 1 |a Su, Chun-Jen  |e verfasserin  |4 aut 
245 1 0 |a Two-dimensional densely packed DNA nanostructure derived from DNA complexation with a low-generation poly(amidoamine) dendrimer 
264 1 |c 2007 
336 |a Text  |b txt  |2 rdacontent 
337 |a ohne Hilfsmittel zu benutzen  |b n  |2 rdamedia 
338 |a Band  |b nc  |2 rdacarrier 
500 |a Date Completed 28.02.2007 
500 |a Date Revised 21.11.2008 
500 |a published: Print 
500 |a Citation Status MEDLINE 
520 |a One of the keys for using deoxyribonucleic acid (DNA) as a nanomaterial relies on how the individual DNA chain can be aligned and how a multitude of DNA chains can be packed into ordered nanostructures. Here we present a simple method for constructing a 2-D densely packed DNA nanostructure using the electrostatic complex of DNA with a poly(amidoamine) (PAMAM) dendrimer of generation two. Ordered DNA arrays are formed by drop-casting an aqueous solution containing positively overcharged complexes onto mica followed by a prolonged incubation. During the incubation, the complexes tend to adsorb onto the negatively charged mica surface through electrostatic attraction. The rodlike complexes organize to form ordered arrays to increase the surface density of the adsorbed complexes and hence the attractive free energy of adsorption. The densely packed nanostructure obtained here is distinguished from the previously reported spheroid or toroid structure derived from DNA complexations with the higher-generation dendrimers 
650 4 |a Journal Article 
650 4 |a Research Support, Non-U.S. Gov't 
650 7 |a Amines  |2 NLM 
650 7 |a Dendrimers  |2 NLM 
650 7 |a Polymers  |2 NLM 
650 7 |a DNA  |2 NLM 
650 7 |a 9007-49-2  |2 NLM 
700 1 |a Liu, Yi-Chun  |e verfasserin  |4 aut 
700 1 |a Chen, Hsin-Lung  |e verfasserin  |4 aut 
700 1 |a Li, Yen-Cheng  |e verfasserin  |4 aut 
700 1 |a Lin, Hsien-Kuang  |e verfasserin  |4 aut 
700 1 |a Liu, Wen-Liang  |e verfasserin  |4 aut 
700 1 |a Hsu, Chain-Shu  |e verfasserin  |4 aut 
773 0 8 |i Enthalten in  |t Langmuir : the ACS journal of surfaces and colloids  |d 1992  |g 23(2007), 3 vom: 30. Jan., Seite 975-8  |w (DE-627)NLM098181009  |x 1520-5827  |7 nnns 
773 1 8 |g volume:23  |g year:2007  |g number:3  |g day:30  |g month:01  |g pages:975-8 
912 |a GBV_USEFLAG_A 
912 |a SYSFLAG_A 
912 |a GBV_NLM 
912 |a GBV_ILN_22 
912 |a GBV_ILN_350 
912 |a GBV_ILN_721 
951 |a AR 
952 |d 23  |j 2007  |e 3  |b 30  |c 01  |h 975-8