CD4(+)CD25(+)FoxP3(+) regulatory T cells suppress Mycobacterium tuberculosis immunity in patients with active disease

CD4(+)CD25(+)FoxP3(+) regulatory T cells suppress Mycobacterium tuberculosis immunity in patients with active disease

CD4(+)CD25(+) regulatory T cells (Treg) play a central role in the prevention of autoimmunity and in the control of immune responses by down-regulating the function of effector CD4(+) or CD8(+) T cells. The role of Treg in Mycobacterium tuberculosis infection and persistence is inadequately document...

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Veröffentlicht in:Clinical immunology (Orlando, Fla.). - 1999. - 123(2007), 1 vom: 17. Apr., Seite 50-9
1. Verfasser: Chen, Xinchun (VerfasserIn)
Weitere Verfasser: Zhou, Boping, Li, Meizhong, Deng, Qunyi, Wu, Xueqiong, Le, Xiaohua, Wu, Chi, Larmonier, Nicolas, Zhang, Wei, Zhang, Hongmei, Wang, Huosheng, Katsanis, Emmanuel
Format: Aufsatz
Sprache:English
Veröffentlicht: 2007
Zugriff auf das übergeordnete Werk:Clinical immunology (Orlando, Fla.)
Schlagworte:Journal Article Research Support, Non-U.S. Gov't Antitubercular Agents Cytokines FOXP3 protein, human Forkhead Transcription Factors Interleukin-2 Receptor alpha Subunit