A 3 x 6 arrayed CCD X-ray detector for continuous rotation method in macromolecular crystallography

A 3 x 6 arrayed charge-coupled device (CCD) X-ray detector has been developed for the continuous-rotation method in macromolecular crystallography at the Photon Factory. The detector has an area of 235.9 mm x 235.9 mm and a readout time of 1.9 s. The detector is made of a 3 x 6 array of identical mo...

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Veröffentlicht in:Journal of synchrotron radiation. - 1994. - 14(2007), Pt 1 vom: 01. Jan., Seite 144-50
1. Verfasser: Ito, Kazuki (VerfasserIn)
Weitere Verfasser: Gaponov, Yurii, Sakabe, Noriyoshi, Amemiya, Yoshiyuki
Format: Aufsatz
Sprache:English
Veröffentlicht: 2007
Zugriff auf das übergeordnete Werk:Journal of synchrotron radiation
Schlagworte:Journal Article Research Support, Non-U.S. Gov't Macromolecular Substances
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520 |a A 3 x 6 arrayed charge-coupled device (CCD) X-ray detector has been developed for the continuous-rotation method in macromolecular crystallography at the Photon Factory. The detector has an area of 235.9 mm x 235.9 mm and a readout time of 1.9 s. The detector is made of a 3 x 6 array of identical modules, each module consisting of a fiber-optic taper (FOT), a CCD sensor and a readout circuit. The outputs from 18 CCDs are read out in parallel and are then digitized by 16-bit analog-to-digital converters. The advantage of this detector over conventional FOT-coupled CCD detectors is the unique CCD readout scheme (frame transfer) which enables successive X-ray exposures to be recorded without interruption of the sample crystal rotation. A full data set of a lysozyme crystal was continuously collected within 360 s (180 degrees rotation, 3 s/1.5 degrees frame). The duty-cycle ratio of the X-ray exposure to the data collection time was almost 100%. The combination of this detector and synchrotron radiation is well suited to rapid and continuous data collection in macromolecular crystallography 
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700 1 |a Gaponov, Yurii  |e verfasserin  |4 aut 
700 1 |a Sakabe, Noriyoshi  |e verfasserin  |4 aut 
700 1 |a Amemiya, Yoshiyuki  |e verfasserin  |4 aut 
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