Clinical evaluation of execution of early goal directed therapy in septic shock

OBJECTIVE: To evaluate the efficacy of early goal directed therapy (EGDT) in septic shock

Bibliographische Detailangaben
Veröffentlicht in:Zhongguo wei zhong bing ji jiu yi xue = Chinese critical care medicine = Zhongguo weizhongbing jijiuyixue. - 1998. - 19(2007), 1 vom: 08. Jan., Seite 14-6
1. Verfasser: He, Zheng-yu (VerfasserIn)
Weitere Verfasser: Gao, Yuan, Wang, Xiang-rui, Hang, Yan-nan
Format: Aufsatz
Sprache:Chinese
Veröffentlicht: 2007
Zugriff auf das übergeordnete Werk:Zhongguo wei zhong bing ji jiu yi xue = Chinese critical care medicine = Zhongguo weizhongbing jijiuyixue
Schlagworte:English Abstract Journal Article Research Support, Non-U.S. Gov't
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245 1 0 |a Clinical evaluation of execution of early goal directed therapy in septic shock 
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500 |a Date Completed 07.07.2009 
500 |a Date Revised 08.01.2007 
500 |a published: Print 
500 |a Citation Status MEDLINE 
520 |a OBJECTIVE: To evaluate the efficacy of early goal directed therapy (EGDT) in septic shock 
520 |a METHODS: Two hundred and three patients with septic shock were assigned into treatment group (n=98) and control group (n=105). According to the state of organ function at the beginning of treatment and multiple organ dysfunction syndrome (MODS) evaluation scores, each group was categorized into three strata: stratum A (mild organ dysfunction), stratum B (medium organ dysfunction) and stratum C (severe organ dysfunction). Mortality and incidence of organ dysfunction in each group were analyzed 
520 |a RESULTS: At stratum A, the mortality and incidence of organ dysfunction in treatment group were significantly lower than those of control group [27.78% (15/54 cases) vs. 37.50% (18/48 cases), 31.48% (17/54 cases) vs. 43.75% (21/48 cases), both P<0.05]. There was no significant difference between treatment group and control group in patients of stratum B [75.86% (22/29 cases) vs. 76.92% (20/26 cases), 55.17% (16/29 cases) vs. 57.69% (15/26 cases)] and stratum C [93.33% (14/15 cases) vs. 96.77% (30/31 cases), 40.00 % (6/15 cases) vs. 41.93% (13/31 cases), all P>0.05] 
520 |a CONCLUSION: In the earlier period of septic shock, EGDT can remarkably decrease the patients'mortality and incidence of organ dysfunction, but can not improve survival rate and prognosis in patients in advanced stage of septic shock 
650 4 |a English Abstract 
650 4 |a Journal Article 
650 4 |a Research Support, Non-U.S. Gov't 
700 1 |a Gao, Yuan  |e verfasserin  |4 aut 
700 1 |a Wang, Xiang-rui  |e verfasserin  |4 aut 
700 1 |a Hang, Yan-nan  |e verfasserin  |4 aut 
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