Support vector machine based training of multilayer feedforward neural networks as optimized by particle swarm algorithm : application in QSAR studies of bioactivity of organic compounds
Multilayer feedforward neural networks (MLFNNs) are important modeling techniques widely used in QSAR studies for their ability to represent nonlinear relationships between descriptors and activity. However, the problems of overfitting and premature convergence to local optima still pose great chall...
| Publié dans: | Journal of computational chemistry. - 1984. - 28(2007), 2 vom: 30. Jan., Seite 519-27 |
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| Auteur principal: | |
| Autres auteurs: | , , , , |
| Format: | Article |
| Langue: | English |
| Publié: |
2007
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| Accès à la collection: | Journal of computational chemistry |
| Sujets: | Journal Article Research Support, Non-U.S. Gov't Cyclooxygenase 2 Inhibitors Imidazoles |