CB2 cannabinoid receptor agonist, JWH-015, triggers apoptosis in immune cells potential role for CB2-selective ligands as immunosuppressive agents

CB2 cannabinoid receptor agonist, JWH-015, triggers apoptosis in immune cells : potential role for CB2-selective ligands as immunosuppressive agents

Cannabinoids are known to interact with CB1 and CB2 receptors expressed in the nervous and immune system, respectively, and mediate a wide range of effects, including anti-inflammatory properties. However, cannabinoids that bind CB1 are also psychoactive thereby limiting their clinical use. In this...

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Bibliographische Detailangaben
Veröffentlicht in:Clinical immunology (Orlando, Fla.). - 1999. - 122(2007), 3 vom: 01. März, Seite 259-70
1. Verfasser: Lombard, Catherine (VerfasserIn)
Weitere Verfasser: Nagarkatti, Mitzi, Nagarkatti, Prakash
Format: Aufsatz
Sprache:English
Veröffentlicht: 2007
Zugriff auf das übergeordnete Werk:Clinical immunology (Orlando, Fla.)
Schlagworte:Journal Article Research Support, N.I.H., Extramural Growth Inhibitors Immunosuppressive Agents Indoles Ligands Mitogens Receptor, Cannabinoid, CB2 JHW 015 W4FL204T10