Immune suppression via IL-4/IL-10-secreting T cells : a nontoxic property of anti-HIV agent trichosanthin

The activity of Trichosanthin (Tk) has been attributed to its toxicity since this plant protein was used as an anti-HIV agent. However, in this study strong inhibition of human lymphoproliferation to soluble and allogeneic antigens was induced by Tk at 0.005-0.5 microg/ml without causing cell damage...

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Bibliographische Detailangaben

Veröffentlicht in:	Clinical immunology (Orlando, Fla.). - 1999. - 122(2007), 3 vom: 01. März, Seite 312-22
1. Verfasser:	Zhou, Hong (VerfasserIn)
Weitere Verfasser:	Jiao, Zhijun, Pan, Jijun, Hong, Jian, Tao, Jiaxian, Li, Ningli, Zhou, Yun, Zhang, Jingwu, Chou, Kuang-Yen
Format:	Aufsatz
Sprache:	English
Veröffentlicht:	2007
Zugriff auf das übergeordnete Werk:	Clinical immunology (Orlando, Fla.)
Schlagworte:	Journal Article Research Support, Non-U.S. Gov't Anti-HIV Agents IL10 protein, human Interleukin-10 130068-27-8 Interleukin-4 207137-56-2 Trichosanthin 60318-52-7