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231223s2006 xx ||||| 00| ||eng c |
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|a (NLM)17073514
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|e rakwb
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|a eng
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|a Boulmedais, F
|e verfasserin
|4 aut
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|a Water-soluble pegylated quantum dots
|b from a composite hexagonal phase to isolated micelles
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|c 2006
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|a Text
|b txt
|2 rdacontent
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|a ohne Hilfsmittel zu benutzen
|b n
|2 rdamedia
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|a Band
|b nc
|2 rdacarrier
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|a Date Completed 07.09.2007
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|a Date Revised 01.12.2018
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|a published: Print
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|a Citation Status MEDLINE
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|a We present a simple method based on the dispersion of fluorescent quantum dots (QD) into a liquid crystal phase that provides either nanostructured material or isolated QD micelles depending on water concentration. The liquid-crystal phase was obtained by using a gallate amphiphile with a poly(ethylene glycol) chain as the polar headgroup, named I. The hydration of QD/I mixtures resulted in the formation of a composite hexagonal phase identified by small-angle X-ray scattering and by polarized light and fluorescence optical microscopy, showing a homogeneous distribution of fluorescence within hexagonal phase. This composite mesophase can be converted into isolated QD-I micelles by dilution in water. The fluorescent QD-I micelles, purified by size exclusion chromatography, are well monodisperse with a hydrodynamic diameter of 20-30 nm. Moreover, these QD do not show any nonspecific adsorption on lipid or cell membranes. By simply adjusting the water content, the PEG gallate amphiphile I provides a simple method to prepare a self-organized composite phase or pegylated water soluble QD micelles for biological applications
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|a Journal Article
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|a Research Support, Non-U.S. Gov't
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|a Lipids
|2 NLM
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|a Micelles
|2 NLM
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|a Water
|2 NLM
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|2 NLM
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|a Polyethylene Glycols
|2 NLM
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|a Bauchat, P
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|a Brienne, M J
|e verfasserin
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|a Arnal, I
|e verfasserin
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|a Artzner, F
|e verfasserin
|4 aut
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|a Gacoin, T
|e verfasserin
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|a Dahan, M
|e verfasserin
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|a Marchi-Artzner, V
|e verfasserin
|4 aut
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| 773 |
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|i Enthalten in
|t Langmuir : the ACS journal of surfaces and colloids
|d 1992
|g 22(2006), 23 vom: 07. Nov., Seite 9797-803
|w (DE-627)NLM098181009
|x 1520-5827
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|g volume:22
|g year:2006
|g number:23
|g day:07
|g month:11
|g pages:9797-803
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