EXAFS characterization of oxaliplatin anticancer drug and its degradation in chloride media

Oxaliplatin is a second-generation platinum-based anticancer drug. Its degradation is studied in solution, in the presence of chloride ions (in neutral or acidic media) in excess. In both cases the degradation product precipitates immediately. The EXAFS spectra of these products show that they are i...

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Veröffentlicht in:Journal of synchrotron radiation. - 1994. - 13(2006), Pt 6 vom: 15. Nov., Seite 477-83
1. Verfasser: Bouvet, Diane (VerfasserIn)
Weitere Verfasser: Michalowicz, Alain, Crauste-Manciet, Sylvie, Curis, Emmanuel, Nicolis, Ioannis, Olivi, Luca, Vlaic, Gilberto, Brossard, Denis, Provost, Karine
Format: Aufsatz
Sprache:English
Veröffentlicht: 2006
Zugriff auf das übergeordnete Werk:Journal of synchrotron radiation
Schlagworte:Journal Article Research Support, Non-U.S. Gov't Antineoplastic Agents Chlorides Organoplatinum Compounds Oxaliplatin 04ZR38536J