Mechanism of HBD-3 deficiency in atopic dermatitis

Mechanism of HBD-3 deficiency in atopic dermatitis

Extrinsic atopic dermatitis (EAD) and intrinsic atopic dermatitis (IAD) patients suffer from recurrent bacterial and viral infections. In this study, we demonstrate significantly decreased expression of human beta defensin (HBD)-3, a potent antimicrobial peptide (AMP), in lesional skin of both IAD (...

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Veröffentlicht in:Clinical immunology (Orlando, Fla.). - 1999. - 121(2006), 3 vom: 15. Dez., Seite 332-8
1. Verfasser: Howell, Michael D (VerfasserIn)
Weitere Verfasser: Boguniewicz, Mark, Pastore, Saveria, Novak, Natalija, Bieber, Thomas, Girolomoni, Giampiero, Leung, Donald Y M
Format: Aufsatz
Sprache:English
Veröffentlicht: 2006
Zugriff auf das übergeordnete Werk:Clinical immunology (Orlando, Fla.)
Schlagworte:Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't Cytokines DEFB103A protein, human Inflammation Mediators beta-Defensins